TTD | Drug: D03ZHE

Drug General Information
Drug ID	D03ZHE
Former ID	DIB013570
Drug Name	MDX-070
Drug Type	Antibody
Indication	Prostate cancer [ICD9: 185; ICD10:C61]		Discontinued in Phase 2	[547384]
Company	Medarex
Target and Pathway
Target(s)	Glutamate carboxypeptidase II	Target Info		[544341]
KEGG Pathway	Alanine, aspartate and glutamate metabolism
	Metabolic pathways
	Vitamin digestion and absorption
NetPath Pathway	TCR Signaling Pathway
NetPath Pathway	TNFalpha Signaling Pathway
Reactome	Amino acid synthesis and interconversion (transamination)
WikiPathways	One Carbon Metabolism
References
Ref 547384	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015769)
Ref 544341	Nanoparticles for Improving Cancer Diagnosis. Mater Sci Eng R Rep. 2013 March; 74(3): 35-69.

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Drug Information