Drug Information

Drug General Information
Drug ID
D03VOM
Former ID
DNC007835
Drug Name
3-(dimethylamino)-1-(4-hexylphenyl)propan-1-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529081]
Formula
C17H27NO
Canonical SMILES
CCCCCCC1=CC=C(C=C1)C(=O)CCN(C)C
InChI
1S/C17H27NO/c1-4-5-6-7-8-15-9-11-16(12-10-15)17(19)13-14-18(2)3/h9-12H,4-8,13-14H2,1-3H3
InChIKey
KDBREDBLOZXWHK-UHFFFAOYSA-N
PubChem Compound ID
3092218
Target and Pathway
Target(s) Thyroid hormone receptor alpha Target Info Inhibitor [529081]
Thyroid hormone receptor beta-1 Target Info Inhibitor [529081]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways Endochondral Ossification
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.
Ref 529081J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships.

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