Drug Information

Drug General Information
Drug ID
D03RTC
Former ID
DIB014140
Drug Name
BMS-812204
Synonyms
CB1 antagonists (obesity), BMS; CB1 antagonists (obesity), Bristol-Myers Squibb
Indication Obesity [ICD9: 278; ICD10:E66] Investigative [543877]
Company
Bristol-Myers Squibb Co
Canonical SMILES
FC(F)(c1nc(c(Cn2c(=O)c(c3cnc(nc3)C)c(c3n2c(=O)n(n3)CC)c<br />2ccc(cc2)Cl)cc1)C)F
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [543877]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543877(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56).
Ref 543877(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 56).

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