Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03RJH
|
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| Former ID |
DNC006297
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| Drug Name |
2,5-bis(2-methoxyphenyl)thiophene
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527907] | ||
| Formula |
C18H16O2S
|
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| Canonical SMILES |
COC1=CC=CC=C1C2=CC=C(S2)C3=CC=CC=C3OC
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| InChI |
1S/C18H16O2S/c1-19-15-9-5-3-7-13(15)17-11-12-18(21-17)14-8-4-6-10-16(14)20-2/h3-12H,1-2H3
|
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| InChIKey |
VXQDFBRKMXPIGY-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527907] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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