Drug Information

Drug General Information
Drug ID
D03RGO
Former ID
DIB005110
Drug Name
CP-331
Synonyms
CP-6
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Terminated [544979]
Company
Zeria Pharmaceutical Co Ltd
Formula
C38H44ClN3O6S
Canonical SMILES
n1(c(c(c2c1ccc(c2)OC)CC(=O)OCCSCC(=O)NCCCOc1cc(CN2CCCCC<br />2)ccc1)C)C(=O)c1ccc(cc1)Cl
CAS Number
CAS 127966-70-5
PubChem Compound ID
130967
Target and Pathway
Target(s) Histamine H2 receptor Target Info Modulator [531237]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Histamine H2 receptor mediated signaling pathway
PathWhiz Pathway Intracellular Signalling Through Histamine H2 Receptor and Histamine
Gastric Acid Production
Reactome Histamine receptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Secretion of Hydrochloric Acid in Parietal Cells
GPCR ligand binding
GPCR downstream signaling
References
Ref 544979Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001767)
Ref 531237Conjugation of chlorin p(6) to histamine enhances its cellular uptake and phototoxicity in oral cancer cells. Cancer Chemother Pharmacol. 2011 Aug;68(2):359-69.

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