Drug Information

Drug General Information
Drug ID
D03PWD
Former ID
DIB014124
Drug Name
GMI-1271
Indication Acute myeloid leukemia [ICD9: 205; ICD10:C92.0] Phase 1 [524962]
Company
Glycomimetics
Target and Pathway
Target(s) E-selectin Target Info Inhibitor [550826]
KEGG Pathway Cell adhesion molecules (CAMs)
TNF signaling pathway
African trypanosomiasis
Malaria
NetPath Pathway IL5 Signaling Pathway
IL4 Signaling Pathway
TNFalpha Signaling Pathway
ID Signaling Pathway
Pathway Interaction Database Thromboxane A2 receptor signaling
Glucocorticoid receptor regulatory network
ATF-2 transcription factor network
Reactome Cell surface interactions at the vascular wall
WikiPathways Human Complement System
TNF alpha Signaling Pathway
Cell surface interactions at the vascular wall
References
Ref 524962ClinicalTrials.gov (NCT02271113) Phase I Study to Assess Safety and Pharmacokinetics of GMI-1271 in Healthy Adult Subjects. U.S. National Institutes of Health.
Ref 550826Clinical pipeline report, company report or official report of glycomimetics.

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