Drug Information

Drug General Information
Drug ID
D03NDD
Former ID
DIB020285
Drug Name
LY466195
Synonyms
LY-466195; LY 466195
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467584]
Formula
C16H24F2N2O4
InChI
InChI=1S/C16H24F2N2O4/c17-16(18)5-13(15(23)24)20(8-16)7-9-1-2-10-6-19-12(14(21)22)4-11(10)3-9/h9-13,19H,1-8H2,(H,21,22)(H,23,24)
InChIKey
OXQXJYQSWZFDBB-UHFFFAOYSA-N
PubChem Compound ID
10168249
PubChem Substance ID
40152401, 78439916, 178101067, 243384990
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Antagonist [543831]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467584(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4250).
Ref 543831(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450).

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