Drug Information

Drug General Information
Drug ID
D03JRO
Former ID
DIB008870
Drug Name
ADCI
Synonyms
SBG-017
Drug Type
Small molecular drug
Indication Epileptic seizures [ICD9: 345.9, 780.3; ICD10:G40, P90, R56] Phase 1 [525718]
Company
National Institutes of Health
Formula
C16H14N2O
Canonical SMILES
C12(NC(c3c1cccc3)Cc1c2cccc1)C(=O)N
CAS Number
CAS 124070-15-1
PubChem Compound ID
130099
Target and Pathway
Target(s) NMDA receptor Target Info Modulator [525718]
Sodium channel Target Info Modulator [525718]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 525718The anticonvulsant SGB-017 (ADCI) blocks voltage-gated sodium channels in rat and human neurons: comparison with carbamazepine. Epilepsia. 2000 Mar;41(3):263-70.
Ref 525718The anticonvulsant SGB-017 (ADCI) blocks voltage-gated sodium channels in rat and human neurons: comparison with carbamazepine. Epilepsia. 2000 Mar;41(3):263-70.

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