Drug Information

Drug General Information
Drug ID
D03HDP
Former ID
DIB001065
Drug Name
ACEA-1416
Synonyms
Glystatin series member (1416), CoCensys
Indication Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63] Terminated [546407]
Company
Purdue Neuroscience Corp
Canonical SMILES
c12c([N+](=O)[O-])c(c(cc2[nH]c(=O)c(=O)[nH]1)Cl)C
CAS Number
CAS 167415-33-0
Target and Pathway
Target(s) NMDA receptor Target Info Modulator [534653]
References
Ref 546407Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007961)
Ref 534653Tolerance develops to the antinociceptive and motor impairing effects of ACEA-1416, a NMDA receptor antagonist, in the formalin and rotarod test in mice. Pharmacol Res. 1998 Apr;37(4):295-302.

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