Drug Information

Drug General Information
Drug ID
D03GDP
Former ID
DNC013413
Drug Name
AM-1715
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529170]
Formula
C25H34O3
Canonical SMILES
CCCCCCC(C)(C)C1=CC2=C(C(=C1)O)C3=C(C=CC(=C3)OC)C(O2)(C)<br />C
InChI
1S/C25H34O3/c1-7-8-9-10-13-24(2,3)17-14-21(26)23-19-16-18(27-6)11-12-20(19)25(4,5)28-22(23)15-17/h11-12,14-16,26H,7-10,13H2,1-6H3
InChIKey
ZNHVPFVYQXICIO-UHFFFAOYSA-N
PubChem Compound ID
24748863
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [529170]
Cannabinoid receptor 2 Target Info Inhibitor [529170]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.

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