Drug Information

Drug General Information
Drug ID
D03AZU
Former ID
DIB016114
Drug Name
Org-31710
Synonyms
Org-31806
Drug Type
Small molecular drug
Indication Contraception [ICD10:Z30] Discontinued in Phase 1 [545237]
Company
Organon BioSciences
Formula
C30H39NO2
Canonical SMILES
C12=C3C(=CC(=O)CC3)[C@@H](C[C@H]1[C@H]1[C@](C[C@@H]2c2c<br />cc(N(C)C)cc2)([C@@]2(OCCC2)CC1)C)C
PubChem Compound ID
164090
Target and Pathway
Target(s) Progesterone receptor Target Info Modulator [526214]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 545237Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002550)
Ref 526214Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells. Fertil Steril. 2001 Dec;76(6):1225-31.

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