TTD | Drug: D02ZCE

Drug General Information
Drug ID	D02ZCE
Former ID	DCL000679
Drug Name	AD-337
Indication	Fibromyalgia; Myalgia; Chemotherapyinduced emesis [ICD9: 729.1, 787; ICD10:M79.1, M79.7, R11]		Phase 1	[536188]
Company	Arakis
Target and Pathway
Target(s)	Sodium-dependent serotonin transporter	Target Info	Modulator	[1572591]
KEGG Pathway	Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
WikiPathways	Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 536188	Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51.
Ref 1572591	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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Drug Information