Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02RPK
|
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| Drug Name |
Z 360
|
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| Synonyms |
Z-360
|
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| Drug Type |
Small molecular drug
|
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| Therapeutic Class |
Anticancer Agents
|
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| Formula |
C29H36N4O5
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gastrin/cholecystokinin type B receptor | Target Info | Modulator | ||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| References | |||||
| Ref 1560000 | Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 production in a cancer-induced pain model in mice.Mol Pain.2010 Oct 28;6:72. | ||||
| Ref 1560439 | Z-360, a novel cholecystokinin-2/gastrin receptor antagonist, inhibits gemcitabine-induced expression of the vascular endothelial growth factor gene in human pancreatic cancer cells. | ||||
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