Drug Information

Drug General Information
Drug ID
D02PKO
Former ID
DNC004460
Drug Name
3-(4-Methoxy-benzenesulfonyl)-cyclopentanethiol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525535]
Formula
C12H16O3S2
Canonical SMILES
COC1=CC=C(C=C1)S(=O)(=O)C2CCC(C2)S
InChI
1S/C12H16O3S2/c1-15-9-2-5-11(6-3-9)17(13,14)12-7-4-10(16)8-12/h2-3,5-6,10,12,16H,4,7-8H2,1H3
InChIKey
JDPMCWHMTGTQGU-UHFFFAOYSA-N
PubChem Compound ID
44294636
Target and Pathway
Target(s) Collagenase 3 Target Info Inhibitor [525535]
NetPath Pathway IL1 Signaling Pathway
PANTHER Pathway Alzheimer disease-presenilin pathway
Plasminogen activating cascade
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
WikiPathways Endochondral Ossification
Activation of Matrix Metalloproteinases
Oncostatin M Signaling Pathway
AGE/RAGE pathway
Matrix Metalloproteinases
References
Ref 525535Bioorg Med Chem Lett. 1999 Jul 5;9(13):1757-60.Synthesis and identification of conformationally constrained selective MMP inhibitors.
Ref 525535Bioorg Med Chem Lett. 1999 Jul 5;9(13):1757-60.Synthesis and identification of conformationally constrained selective MMP inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.