Drug Information

Drug General Information
Drug ID
D02NSY
Former ID
DIB018943
Drug Name
Banyu Compound-24
Synonyms
C-24
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542383]
Formula
C27H35N3O2
InChI
InChI=1S/C27H35N3O2/c31-26(25-12-6-17-30(25)20-22-8-2-1-3-9-22)28-15-7-16-29-18-13-27(14-19-29)24-11-5-4-10-23(24)21-32-27/h1-5,8-11,25H,6-7,12-21H2,(H,28,31)/t25-/m1/s1
InChIKey
MAKMQGKJURAJEN-RUZDIDTESA-N
PubChem Compound ID
10296561
PubChem Substance ID
15303254, 22671134, 35613876, 74464733, 103478124, 104066231, 135653184, 136368061, 144115681, 152344160, 164043467, 178103933
Target and Pathway
Target(s) Nociceptin receptor Target Info Antagonist [530141]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 542383(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7361).
Ref 530141Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24. Eur J Pharmacol. 2009 Jul 1;614(1-3):50-7.

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