Drug Information

Drug General Information
Drug ID
D02KAF
Former ID
DIB011815
Drug Name
GT-2203
Synonyms
GT-2144; GT-2203; GT-2204; GT-2223; GT-2328; GT-2396; GT-2397; GT-2431; H3 agonists, Gliatech
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [546559]
Company
Gliatech Inc
Canonical SMILES
[C@H]1(C[C@H]1N)c1nc[nH]c1
Target and Pathway
Target(s) Histamine H3 receptor Target Info Agonist [543673]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 546559Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008938)
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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