Drug Information

Drug General Information
Drug ID
D02HKL
Former ID
DIB004125
Drug Name
Suriclone
Synonyms
Suril; RP-31264
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Discontinued in Preregistration [544682]
Company
Rhone-Poulenc SA
Formula
C20H20ClN5O3S2
Canonical SMILES
N1(C(C2=C(C1=O)SCCS2)OC(=O)N1CCN(CC1)C)c1nc2nc(ccc2cc1)<br />Cl
CAS Number
CAS 53813-83-5
PubChem Compound ID
40903
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [553196]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 544682Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000574)
Ref 553196The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines. Naunyn Schmiedebergs Arch Pharmacol. 1994 Sep;350(3):294-300.

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