Drug Information

Drug General Information
Drug ID
D02HCU
Former ID
DIB006289
Drug Name
WEB-2347
Drug Type
Small molecular drug
Indication Allergy [ICD9: 995.3; ICD10:T78.4] Terminated [544959]
Company
Boehringer Ingelheim Corp
Formula
C25H28ClN5OS
Canonical SMILES
c12c(n3c(nnc3)CN=C2c2c(Cl)cccc2)sc2c1CC(C(=O)N(CCC)CCC)<br />C2
CAS Number
CAS 114800-19-0
PubChem Compound ID
3081067
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Modulator [529756]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 544959Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001720)
Ref 529756WEB 2347: pharmacology of a new very potent and long acting hetrazepinoic PAF-antagonist and its action in repeatedly sensitized guinea-pigs. J Lipid Mediat. 1991 Jul-Aug;4(1):39-44.

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