TTD | Drug: D02EZF

Drug General Information
Drug ID	D02EZF
Former ID	DIB020963
Drug Name	SMP-797
Synonyms	compound 22b [PMID: 16242323]
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527814]
Formula	C34H43N5O4
InChI	InChI=1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)
InChIKey	HNRUUMLUBDTZHX-UHFFFAOYSA-N
PubChem Compound ID	9938311
PubChem Substance ID	14911493, 24211828, 74396333, 103696092, 104061443, 104139818, 139166482, 178103340, 198976081, 223370016, 225104491, 228950663, 247941717, 248267189
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Modulator
KEGG Pathway	Drug metabolism - other enzymes
KEGG Pathway	Metabolic pathways
Pathway Interaction Database	E2F transcription factor network
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450
References
Ref 527814	Bioorg Med Chem Lett. 2006 Jan 1;16(1):44-8. Epub 2005 Oct 18.Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility.

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Drug Information