Drug Information

Drug General Information
Drug ID
D02DTQ
Former ID
DIB016648
Drug Name
PF-3893787
Synonyms
PF-03893787; PF-3826719
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Phase 1 [531625]
Company
Pfizer Inc
Formula
C13H22N6
Canonical SMILES
c1(nc(cc(n1)N1C[C@@H](CC1)NC)NCC1CC1)N
PubChem Compound ID
24745335
Target and Pathway
Target(s) Histamine H4 receptor Target Info Antagonist [531625]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 531625Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.
Ref 531625Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor antagonist. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6596-602.

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