Drug Information

Drug General Information
Drug ID
D02BBN
Former ID
DNC014620
Drug Name
4-Amino-3-benzofuran-2-yl-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533413]
Formula
C12H13NO3
Canonical SMILES
C1=CC=C2C(=C1)C=C(O2)C(CC(=O)O)CN
InChI
1S/C12H13NO3/c13-7-9(6-12(14)15)11-5-8-3-1-2-4-10(8)16-11/h1-5,9H,6-7,13H2,(H,14,15)
InChIKey
SRLRWPSSQWUHQC-UHFFFAOYSA-N
PubChem Compound ID
129512
Target and Pathway
Target(s) Gamma-aminobutyric acid B receptor Target Info Inhibitor [533413]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
GABAergic synapse
Estrogen signaling pathway
Morphine addiction
Reactome Activation of G protein gated Potassium channels
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Potassium Channels
GPCR ligand binding
GPCR downstream signaling
References
Ref 533413J Med Chem. 1987 Apr;30(4):743-6.Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.
Ref 533413J Med Chem. 1987 Apr;30(4):743-6.Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.