Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02BBJ
|
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| Former ID |
DNC006480
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| Drug Name |
5-hydroxy-2-(4-methylaminophenyl)benzofuran
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528159] | ||
| Formula |
C15H13NO2
|
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| Canonical SMILES |
CNC1=CC=C(C=C1)C2=CC3=C(O2)C=CC(=C3)O
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| InChI |
1S/C15H13NO2/c1-16-12-4-2-10(3-5-12)15-9-11-8-13(17)6-7-14(11)18-15/h2-9,16-17H,1H3
|
||||
| InChIKey |
ZNESXKIPTICLME-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528159] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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