Drug Information

Drug General Information
Drug ID
D01TSX
Former ID
DNC013349
Drug Name
(R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528778]
Formula
C11H16INO2
Canonical SMILES
CC(CC1=CC(=C(C=C1OC)I)OC)N
InChI
1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
InChIKey
BGMZUEKZENQUJY-SSDOTTSWSA-N
PubChem Compound ID
9840090
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [528778]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528778Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. Epub 2007 Mar 25.Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.
Ref 528778Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. Epub 2007 Mar 25.Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.

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