Drug Information

Drug General Information
Drug ID
D01SPJ
Former ID
DIB009765
Drug Name
Litenimod
Synonyms
Li-28; CpG oligonucleotide immunomodulator (cancer), Oligovax
Indication Glioblastoma multiforme [ICD9: 191; ICD10:C71] Phase 1 [551464]
Company
Oligovax SAS
Formula
C256H322N95O129P25S25
PubChem Compound ID
56841944
Target and Pathway
Target(s) Toll-like receptor 9 Target Info Modulator [543477]
KEGG Pathway Toll-like receptor signaling pathway
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Tuberculosis
Measles
Herpes simplex infection
NetPath Pathway BCR Signaling Pathway
PANTHER Pathway Toll receptor signaling pathway
Reactome PI3K Cascade
Trafficking and processing of endosomal TLR
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 dependent cascade initiated on endosome
WikiPathways Toll-like receptor signaling pathway
Toll-Like Receptors Cascades
MyD88 dependent cascade initiated on endosome
Trafficking and processing of endosomal TLR
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Regulation of toll-like receptor signaling pathway
References
Ref 551464Clinical pipeline report, company report or official report of Oligovax SAS.
Ref 543477(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1759).

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