TTD | Drug: D01RTR

Drug General Information
Drug ID	D01RTR
Former ID	DNC008265
Drug Name	(R)-3-(2-(2-methylpyrrolidin-1-yl)ethyl)pyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529212]
Formula	C12H18N2
Canonical SMILES	CC1CCCN1CCC2=CN=CC=C2
InChI	1S/C12H18N2/c1-11-4-3-8-14(11)9-6-12-5-2-7-13-10-12/h2,5,7,10-11H,3-4,6,8-9H2,1H3/t11-/m1/s1
InChIKey	WJLLZUXQRCOTAJ-LLVKDONJSA-N
PubChem Compound ID	44455920
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[529212]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529212	Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. Epub 2007 Oct 24.In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.
Ref 529212	Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. Epub 2007 Oct 24.In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.

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Drug Information