Drug Information

Drug General Information
Drug ID
D01PPZ
Former ID
DNC012425
Drug Name
Ridine-5-carboxylic acid ethyl ester
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533164]
Formula
C16H24N4O2
Canonical SMILES
CCC(C)CCN1C2=NC(=C(C(=C2C=N1)N)C(=O)OCC)C
InChI
1S/C16H24N4O2/c1-5-10(3)7-8-20-15-12(9-18-20)14(17)13(11(4)19-15)16(21)22-6-2/h9-10H,5-8H2,1-4H3,(H2,17,19)
InChIKey
YWSGZSUSPFMIIN-UHFFFAOYSA-N
PubChem Compound ID
14590509
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533164]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533164]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [533164]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533164]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP706:SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 533164J Med Chem. 1989 Dec;32(12):2561-73.Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents.
Ref 533164J Med Chem. 1989 Dec;32(12):2561-73.Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents.

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