Drug Information

Drug General Information
Drug ID
D01OFY
Former ID
DIB008040
Drug Name
LAS-31180
Drug Type
Small molecular drug
Indication Heart failure [ICD9: 428; ICD10:I50] Terminated [525948]
Company
Almirall Prodesfarma SA
Formula
C11H12N2O3S
Canonical SMILES
CN1C=C(C(=O)C2=CC=CC=C21)NS(=O)(=O)C
InChI
1S/C11H12N2O3S/c1-13-7-9(12-17(2,15)16)11(14)8-5-3-4-6-10(8)13/h3-7,12H,1-2H3
InChIKey
LSIYNVMXGMDGMG-UHFFFAOYSA-N
PubChem Compound ID
195841
PubChem Substance ID
10262120, 15416533, 33516123, 50815678, 57398376, 103831363, 113461651, 117631837, 125718071, 128534743, 135173899, 232921059
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Modulator [525948]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 525948Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6.
Ref 525948Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6.

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