Drug Information

Drug General Information
Drug ID
D01NTN
Former ID
DNC005483
Drug Name
3-(3,5-Dibromo-4-hexyloxy-phenyl)-propionic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527532]
Formula
C15H20Br2O3
Canonical SMILES
CCCCCCOC1=C(C=C(C=C1Br)CCC(=O)O)Br
InChI
1S/C15H20Br2O3/c1-2-3-4-5-8-20-15-12(16)9-11(10-13(15)17)6-7-14(18)19/h9-10H,2-8H2,1H3,(H,18,19)
InChIKey
FVDRTJXVCUAOCA-UHFFFAOYSA-N
PubChem Compound ID
11350323
Target and Pathway
Target(s) Thyroid hormone receptor alpha Target Info Inhibitor [527532]
Thyroid hormone receptor beta-1 Target Info Inhibitor [527532]
KEGG Pathway Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction
Thyroid hormone signaling pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
WikiPathways Endochondral Ossification
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Nuclear Receptors
References
Ref 527532J Med Chem. 2005 May 5;48(9):3114-7.Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor.
Ref 527532J Med Chem. 2005 May 5;48(9):3114-7.Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.