Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01LEV
|
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| Former ID |
DNC007474
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| Drug Name |
3-((3-bromothiophen-2-yl)methylene)indolin-2-one
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528681] | ||
| Formula |
C13H8BrNOS
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CC3=C(C=CS3)Br)C(=O)N2
|
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| InChI |
1S/C13H8BrNOS/c14-10-5-6-17-12(10)7-9-8-3-1-2-4-11(8)15-13(9)16/h1-7H,(H,15,16)/b9-7+
|
||||
| InChIKey |
ZGCKMTQNGWQKEN-VQHVLOKHSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | Inhibitor | [528681] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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