Drug Information

Drug General Information
Drug ID
D01EHP
Former ID
DNC003781
Drug Name
Cyclopentyl-(9-methyl-9H-purin-6-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529774]
Formula
C11H15N5
Canonical SMILES
CN1C=NC2=C1N=CN=C2NC3CCCC3
InChI
1S/C11H15N5/c1-16-7-14-9-10(12-6-13-11(9)16)15-8-4-2-3-5-8/h6-8H,2-5H2,1H3,(H,12,13,15)
InChIKey
LZMRVYPPUVMKOI-UHFFFAOYSA-N
PubChem Compound ID
4401
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [529774]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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