Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01CDL
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| Former ID |
DNC003560
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| Drug Name |
L-652731
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [526814] | ||
| Formula |
C22H28O7
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| Canonical SMILES |
COC1=CC(=C(C=C1C2CCC(O2)C3=CC(=C(C=C3OC)OC)OC)OC)OC
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| InChI |
1S/C22H28O7/c1-23-17-11-21(27-5)19(25-3)9-13(17)15-7-8-16(29-15)14-10-20(26-4)22(28-6)12-18(14)24-2/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m1/s1
|
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| InChIKey |
BNAYTLLYBCCIOF-HZPDHXFCSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Platelet-activating factor receptor | Target Info | Inhibitor | [526814] | |
| NetPath Pathway | IL5 Signaling Pathway | ||||
| Leptin Signaling Pathway | |||||
| References | |||||
| Ref 526814 | J Med Chem. 1992 Sep 18;35(19):3474-82.Development, synthesis, and biological evaluation of (-)-trans-(2S,5S)-2-[3-[(2-oxopropyl)sulfonyl]-4-n-propoxy-5-(3- hydroxypropoxy)-phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent orally active platelet-activating factor (PAF) antagonist and its water-soluble prodrug phosphate ester. | ||||
| Ref 526814 | J Med Chem. 1992 Sep 18;35(19):3474-82.Development, synthesis, and biological evaluation of (-)-trans-(2S,5S)-2-[3-[(2-oxopropyl)sulfonyl]-4-n-propoxy-5-(3- hydroxypropoxy)-phenyl]-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a potent orally active platelet-activating factor (PAF) antagonist and its water-soluble prodrug phosphate ester. | ||||
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