Drug Information

Drug General Information
Drug ID
D01AGR
Former ID
DNC008885
Drug Name
1-[5-(4-Chlorophenyl)-2-furoyl]piperazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529491]
Formula
C15H15ClN2O2
PubChem Compound ID
24857857
Target and Pathway
Target(s) PN3 Na+ channel Target Info Inhibitor [529491]
Voltage-gated sodium channel subunit alpha Nav1.8 Target Info Inhibitor [529491]
Sodium channel protein type 5 subunit alpha Target Info Inhibitor [529491]
KEGG Pathway Adrenergic signaling in cardiomyocytes
PathWhiz Pathway Muscle/Heart Contraction
Reactome Interaction between L1 and AnkyrinsR-HSA-445095:Interaction between L1 and Ankyrins
WikiPathways SIDS Susceptibility Pathways
Cardiac Progenitor Differentiation
References
Ref 529491Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. Epub 2008 May 6.Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.
Ref 529491Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. Epub 2008 May 6.Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.

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