Drug Information

Drug General Information
Drug ID
D00ZGW
Former ID
DNC010724
Drug Name
GSK-325971A
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530767]
Formula
C18H19ClN4O
Canonical SMILES
CCN1C2=NC=C(C(=C2C=N1)Cl)C(=O)NCC3=C(C=C(C=C3)C)C
InChI
1S/C18H19ClN4O/c1-4-23-17-14(10-22-23)16(19)15(9-20-17)18(24)21-8-13-6-5-11(2)7-12(13)3/h5-7,9-10H,4,8H2,1-3H3,(H,21,24)
InChIKey
XLMANSLWCIMZAE-UHFFFAOYSA-N
PubChem Compound ID
46883841
Target and Pathway
Target(s) Progesterone receptor Target Info Inhibitor [530767]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 530767Bioorg Med Chem Lett. 2010 Apr 1;20(7):2340-3. Epub 2010 Feb 4.The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist.
Ref 530767Bioorg Med Chem Lett. 2010 Apr 1;20(7):2340-3. Epub 2010 Feb 4.The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist.

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