Drug Information

Drug General Information
Drug ID
D00UPU
Former ID
DIB000444
Drug Name
RPR-107836
Synonyms
IDDB8561
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Investigative [543961]
Company
Rhone-Poulenc Rorer Inc
Canonical SMILES
N1([C@H](SC[C@H]1C(=O)OC(C)(C)C)c1c(F)cccc1)C(=O)CNC(=O<br />)Nc1cc([C@@H](C(=O)O)OC)ccc1
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info Modulator [543961]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543961(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 77).
Ref 543961(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 77).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.