Drug Information

Drug General Information
Drug ID
D00PYW
Former ID
DNC004238
Drug Name
4-[2-(4-Imidazol-1-yl-phenoxy)-ethyl]-morpholine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526913]
Formula
C15H19N3O2
Canonical SMILES
C1COCCN1CCOC2=CC=C(C=C2)N3C=CN=C3
InChI
1S/C15H19N3O2/c1-3-15(4-2-14(1)18-6-5-16-13-18)20-12-9-17-7-10-19-11-8-17/h1-6,13H,7-12H2
InChIKey
PXFGMZGVHWPLCC-UHFFFAOYSA-N
PubChem Compound ID
44341256
Target and Pathway
Target(s) Cytochrome P450 3A4 Target Info Inhibitor [526913]
Cytochrome P450 2D6 Target Info Inhibitor [526913]
KEGG Pathway Steroid hormone biosynthesis
Linoleic acid metabolism
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Metabolic pathways
Bile secretion
Chemical carcinogenesishsa00980:Metabolism of xenobiotics by cytochrome P450
Serotonergic synapse
PathWhiz Pathway Caffeine Metabolism
Retinol Metabolism
Reactome Xenobiotics
Aflatoxin activation and detoxificationR-HSA-211981:Xenobiotics
WikiPathways Metapathway biotransformation
Aflatoxin B1 metabolism
Estrogen metabolism
Benzo(a)pyrene metabolism
Tamoxifen metabolism
Tryptophan metabolism
Oxidation by Cytochrome P450
Nuclear Receptors in Lipid Metabolism and Toxicity
Nuclear Receptors Meta-Pathway
Farnesoid X Receptor Pathway
Vitamin D Receptor Pathway
Felbamate Metabolism
Lidocaine metabolism
Nifedipine Activity
Colchicine Metabolic Pathway
Irinotecan Pathway
Drug Induction of Bile Acid Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine MetabolismWP702:Metapathway biotransformation
Aripiprazole Metabolic Pathway
Codeine and Morphine Metabolism
References
Ref 526913Bioorg Med Chem Lett. 2004 Jan 19;14(2):333-6.Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors.
Ref 526913Bioorg Med Chem Lett. 2004 Jan 19;14(2):333-6.Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors.

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