Drug Information

Drug General Information
Drug ID
D00LCT
Former ID
DIB005003
Drug Name
Symakalim
Synonyms
EMD-57283
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 1 [545492]
Company
Merck KGaA
Canonical SMILES
C1(c2c(OC(C1O)(C)C)ccc(C#N)c2)Oc1nn(c(=O)cc1)C
Target and Pathway
Target(s) Potassium channel Target Info Agonist [534618]
References
Ref 545492Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003464)
Ref 534618Synthesis and antihypertensive activity of 4-(diazabicyclo[4.1.0]-heptenyloxy)benzopyran derivatives and their analogues. Chem Pharm Bull (Tokyo). 1998 Apr;46(4):602-9.

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