Drug Information

Drug General Information
Drug ID
D00IGI
Former ID
DNC004971
Drug Name
2-Amino-4-phosphono-butyric acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527336]
Formula
C4H10NO5P
Canonical SMILES
C(CP(=O)(O)O)C(C(=O)O)N
InChI
1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
InChIKey
DDOQBQRIEWHWBT-UHFFFAOYSA-N
PubChem Compound ID
2207
Target and Pathway
Target(s) Metabotropic glutamate receptor 8 Target Info Inhibitor [527336]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 527336Bioorg Med Chem Lett. 2005 Jan 17;15(2):349-51.(2S,1'S,2'R,3'R)-2(2'-Carboxy-3'-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors.
Ref 527336Bioorg Med Chem Lett. 2005 Jan 17;15(2):349-51.(2S,1'S,2'R,3'R)-2(2'-Carboxy-3'-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors.

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