Drug Information

Drug General Information
Drug ID
D00FKJ
Former ID
DNC009443
Drug Name
(1S,2R)-N-Oleoylcyclopropanolamide
Indication Discovery agent Investigative [530070]
Canonical SMILES
CCCCCCCCCCCCCCCC(=O)NC1CC1O
InChI
1S/C19H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)20-17-16-18(17)21/h17-18,21H,2-16H2,1H3,(H,20,22)/t17-,18+/m1/s1
InChIKey
LIBNBUULGCFJNR-MSOLQXFVSA-N
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [530070]
Cannabinoid receptor 1 Target Info Inhibitor [530070]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 530070J Med Chem. 2009 May 14;52(9):3001-9.Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Ref 530070J Med Chem. 2009 May 14;52(9):3001-9.Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.

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