Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00DFR
|
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| Former ID |
DNC006741
|
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| Drug Name |
(5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528191] | ||
| Formula |
C20H20O3
|
||||
| Canonical SMILES |
C1C=CC(=O)C(C1OCC2=CC=CC=C2)OCC3=CC=CC=C3
|
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| InChI |
1S/C20H20O3/c21-18-12-7-13-19(22-14-16-8-3-1-4-9-16)20(18)23-15-17-10-5-2-6-11-17/h1-12,19-20H,13-15H2/t19-,20-/m1/s1
|
||||
| InChIKey |
PHZAKVRYDXRMRQ-WOJBJXKFSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gamma-secretase | Target Info | Inhibitor | [528191] | |
| Presenilin 1 | Target Info | Inhibitor | [528191] | ||
| Presenilin 2 | Target Info | Inhibitor | [528191] | ||
| NetPath Pathway | Notch Signaling Pathway | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| NOTCH2 Activation and Transmission of Signal to the Nucleus | |||||
| EPH-ephrin mediated repulsion of cellsR-HSA-1474228:Degradation of the extracellular matrixR-HSA-1251985:Nuclear signaling by ERBB4 | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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