Drug Information

Drug General Information
Drug ID
D00BKV
Former ID
DIB015189
Drug Name
SB 418790
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Discontinued in Phase 1 [547143]
Company
Asahi Kasei Pharma
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Agonist [551185]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 547143Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013384)
Ref 551185News and Analysis. Nature Reviews Drug Discovery 1, 257-258 (April 2002).

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