Target Information

Target General Infomation
Target ID
T32612
Former ID
TTDC00212
Target Name
Cyclin-dependent kinase
Synonyms
Cell division protein kinase; Cyclin-dependent protein kinase
Target Type
Discontinued
Disease Cancer [ICD9: 140-229; ICD10: C00-C96]
Chronic lymphocytic leukaemia [ICD10: C91]
BioChemical Class
Kinase
Target Validation
T32612
EC Number
EC 2.7.1.-
Drugs and Mode of Action
Drug(s) Flavopiridol Drug Info Discontinued in Phase 3 Chronic lymphocytic leukaemia [537114], [541024]
Inhibitor BS-194 Drug Info [542984]
Flavopiridol Drug Info [549823]
References
Ref 537114Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
Ref 541024(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5680).
Ref 542984(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8176).
Ref 549823Pharma & Vaccines. Product Development Pipeline. April 29 2009.

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