Target General Information
Target ID	T77594
Target Name	Glucose regulated protein 78 kDa
Synonyms	Endoplasmic reticulum lumenal Ca(2+)binding protein grp78; GRP78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chainbinding protein; HSPA5
Target Type	Clinical Trial
Gene Name	HSPA5
Biochemical Class	Heat shock protein
UniProt ID	GRP78_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Melanoma
Example drug	SAM-6			Phase 1	[524124], [1572592]
Tissue	Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.09 Z-score: 0.16 P-value: 7.97E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 524124	ClinicalTrials.gov (NCT01727778) Safety and Preliminary Efficacy Study of the Antibody PAT-SM6 in Patients With Relapsed or Refractory Multiple Myeloma. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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