Target General Information
Target ID	T76198
Target Name	Thromboxane A2 receptor
Synonyms	Prostanoid TP receptor; TXA2 receptor; TXA2-R; TBXA2R
Target Type	Successful
Gene Name	TBXA2R
Biochemical Class	GPCR rhodopsin
UniProt ID	TA2R_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	KP-496			Phase 2	[528550], [1572592]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.11 Z-score: -0.31 P-value: 2.78E-04
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 528550	Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea. Allergol Int. 2006 Dec;55(4):403-10.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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