Target General Information
Target ID	T14558
Target Name	Tryptase
Synonyms	Tryptase I; Tryptase alpha-1; Tryptase alpha/beta-1; TPSAB1
Target Type	Successful
Gene Name	TPSAB1
Biochemical Class	Peptidase
UniProt ID	TRYB1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	APC-366			Discontinued in Phase 2	[545523], [1572592]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 1.07 Z-score: 0.89 P-value: 3.09E-07
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 545523	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003595)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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