Drug Information

Drug General Information
Drug ID
D0F1OG
Former ID
DIB006300
Drug Name
Soluble ErbB3 theragnostics
Synonyms
Soluble ErbB3 theragnostics (cancer); SErbB3 theragnostics (cancer), TBIG; SHer theragnostics (cancer), TBIG;Soluble ErbB3 theragnostics (cancer), TBIG; Soluble Her theragnostics (cancer), TBIG; P85-sErbB3 (cancer), TBIG
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543486]
Company
Tumor Biology Investment Group Inc
Target and Pathway
Target(s) Receptor protein-tyrosine kinase erbB-3 Target Info Inhibitor [543486]
KEGG Pathway ErbB signaling pathway
Calcium signaling pathway
Endocytosis
Proteoglycans in cancer
MicroRNAs in cancer
NetPath Pathway TNFalpha Signaling Pathway
PANTHER Pathway Cadherin signaling pathway
EGF receptor signaling pathway
Pathway Interaction Database ErbB2/ErbB3 signaling events
ErbB receptor signaling network
a6b1 and a6b4 Integrin signaling
WikiPathways ErbB Signaling Pathway
Apoptosis-related network due to altered Notch3 in ovarian cancer
Signaling Pathways in Glioblastoma
miR-targeted genes in muscle cell - TarBase
Heart Development
References
Ref 543486(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1798).
Ref 543486(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1798).

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