Drug Information

Drug General Information
Drug ID
D06XVF
Former ID
DCL001106
Drug Name
CBT-1
Indication Non-small cell lung cancer [ICD10:C33-C34] Phase 3 [521968]
Company
National Institutes of Health Clinical Center (CC)
Target and Pathway
Target(s) Multidrug resistance protein 1 Target Info Modulator
KEGG Pathway ABC transporters
Bile secretion
MicroRNAs in cancer
NetPath Pathway IL2 Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome ABC-family proteins mediated transport
WikiPathways Nuclear Receptors in Lipid Metabolism and Toxicity
Abacavir transport and metabolism
Multi Drug Resistance Protein 1 (Glycoprotein 1) Regulation
Integrated Pancreatic Cancer Pathway
Allograft Rejection
Drug Induction of Bile Acid Pathway
Codeine and Morphine Metabolism
References
Ref 521968ClinicalTrials.gov (NCT00437749) A Study of CBT-1 and Paclitaxel With Carboplatin in Patients With Advanced Inoperable Non-small Cell Lung Cancer. U.S. National Institutes of Health.

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