Drug Information

Drug General Information
Drug ID
D0V7US
Former ID
DIB006681
Drug Name
NKP 608
Synonyms
AV608)
Indication Mood disorder [ICD10:F30-F39] Phase 2 [531755]
Company
Novartis; Avera Pharmaceuticals
Target and Pathway
Target(s) Substance-P receptor Target Info Antagonist [531755]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 531755Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study. Aliment Pharmacol Ther.2012 Feb;35(3):360-7.
Ref 531755Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study. Aliment Pharmacol Ther.2012 Feb;35(3):360-7.

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