Drug Information

Drug General Information
Drug ID
D07NDL
Former ID
DIB000524
Drug Name
Short-acting etomidate analogue
Synonyms
MOC-etomidate; Short-acting etomidate analogue (general anesthesia); Short-acting etomidate analogue (general anesthesia), Massachusetts General Hospital
Indication General anesthesia [ICD9: 338; ICD10:R20.0] Investigative [543814]
Company
Massachusetts General Hospital
Canonical SMILES
c1ncc(n1[C@H](C)c1ccccc1)C(=O)OCCC(=O)OC
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [543814]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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