Drug Information

Drug General Information
Drug ID
D02OCD
Former ID
DIB009924
Drug Name
NIBR-785
Drug Type
Small molecular drug
Indication Multiple scierosis [ICD9: 340; ICD10:G35] Investigative [543701]
Company
Novartis Institutes for BioMedical Research Inc
Formula
C22H24N2O5
Canonical SMILES
CC(C)(c1ccc(NC(=O)c2c(=O)oc3c(c(ccc3c2)OC)OCC)cc1)N
PubChem Compound ID
46184240
Target and Pathway
Target(s) Sphingosine 1-phosphate receptor 1 Target Info Modulator [543701]
KEGG Pathway FoxO signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
IL2 Signaling Pathway
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
S1P3 pathway
S1P1 pathway
Sphingosine 1-phosphate (S1P) pathway
PDGFR-beta signaling pathway
Reactome G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Signal Transduction of S1P Receptor
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543701(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).
Ref 543701(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.