Drug Information

Drug General Information
Drug ID
D0VO5S
Former ID
DIB000054
Drug Name
LY-2584702
Synonyms
LY-S6K1; LY-S6K1 HCl; LY-S6K1 tosylate; P70 S6 kinase inhibitor (cancer), Eli Lilly
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [523253], [543009]
Company
Eli Lilly & Co
Formula
C21H19F4N7
InChI
InChI=1S/C21H19F4N7/c1-31-10-17(13-2-3-16(22)15(8-13)21(23,24)25)29-19(31)12-4-6-32(7-5-12)20-14-9-28-30-18(14)26-11-27-20/h2-3,8-12H,4-7H2,1H3,(H,26,27,28,30)
InChIKey
FYXRSVDHGLUMHB-UHFFFAOYSA-N
PubChem Compound ID
25118925
PubChem Substance ID
56443143, 81004928, 137667004, 172650735, 198940186, 223705444, 224287815, 226650534, 242863685, 245772292, 248365708, 249565928, 251910740, 252551999
Target and Pathway
Target(s) S6K kinase Target Info Modulator
References
Ref 523253ClinicalTrials.gov (NCT01241461) A Study of LY2584702 in Solid Tumors. U.S. National Institutes of Health.
Ref 543009(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8248).

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